Faculty member:

Pedro Esteban Maldonado Arbogast

pedro@uchile.cl

Education:

  • Biólogo de la Universidad de Chile, 1984.
  • Magíster en Ciencias Biológicas, mención Fisiología. Universidad de Chile, 1986
  • Doctor en Fisiología. Universidad de Pennsylvania, EE.UU., 1993.

Position:

Profesor Titular Departamento de Neurociencias Facultad de Medicina

PUBLICATIONS

  1. Maldonado P.E., Maturana H. & Varela F. Frontal and lateral visual systems in birds. Brain, Behavior and Evolution. 32:57-62 (1988)

  2. Maldonado P.E., Rose B. & Loewenstein W.R. Growth factors modulate junctional communication. J. Membrane Biology. 106:203-210 (1988)

  3. Gray C.M, Maldonado P.E., Wilson M. and McNaughton B. Tetrodes Markedly Improve the Reliability and Yield of Multiple Single Unit Isolation from Multiunit Recordings in Cat Striate Cortex. J. Neurosci. Methods. 63:43-54. (1995)

  4. Maldonado P.E. & C.M. Gray. Heterogeneity in local distribution of orientation selective neurons in the cat primary visual cortex. Visual Neuroscience 13: 509-516 (1996)

  5. Maldonado P.E., J.Altman & G.L.Gerstein. Neuronal afterdischarges in the rat auditory cortex and cortical electrical microstimulation. Sechenov Pysiological Journal. 82:3-17 (1996)

  6. Maldonado, P.E. & Gerstein, G.L. Reorganization in the auditory cortex of the rat induced by intracortical microstimulation: a multiple single-unit Study. Experimental Brain Research. 112:420-430 (1996)

  7. Maldonado P.E., & Gerstein G.L. Neuronal Assemblies Dynamics in the rat auditory cortex during reorganization induced by intracortical microstimulation. Experimental Brain Research. 112:431-441 (1996)

  8. Maldonado P.E., Gödecke I., Gray C.M. & Bonhoeffer T. Microscopic organization of orientation preferences in the cat striate cortex. Science 276:1551-1555 (1997)

  9. G.L. Gerstein, M.J. Bloom and P.E. Maldonado. (1997) Organization and perturbation of neuronal assemblies. In: Central Auditory Processing and Neural Modeling. Eds.: J. Brugge and P. Poon, Plenum.

  10. Maldonado P.E., Altman J.A. & Gerstein GL (1998) Neuron discharges in the rat auditory cortex during electrical intracortical stimulation. Neurosci. Behav Physiol. 28(1): 48-59.

  11. Maldonado P. “Neuronas de la corteza visual: Orientación selectiva” Investigación y Ciencia (Spanish Edition of Scientific American), Jan 1999 P. 37

  12. Friedman-Hill S.R., Maldonado P.E. & Gray C.M. (2000) Temporal Dynamics of Neuronal Activity in the Striate Cortex of Alert Macaque: I. Incidence and Stimulus-Dependence of Oscillations. Cerebral Cortex 10:1105-1116

  13. Maldonado P.E., Friedman-Hill S.R. & Gray C.M (2000) Temporal Dynamics of Neuronal Activity in the Striate Cortex of Alert Macaque: II. Short and Long-Range Temporally-Correlated Activity. Cerebral Cortex 10:1117-1131

  14. Vivaldi E. & Maldonado P.E. (2001) Computadores en investigación biomédica: I. Análisis de señales bioeléctricas. Rev. Medica de Chile 129:955-962

  15. Maldonado P.E. & Vivaldi E. (2001) Computadores en investigación biomédica: II. Control experimental, adquisición y almacenaje de datos. Rev. Medica de Chile 129:1085-1092

  16. Goldman M., Maldonado P.E., Abbott L.F. (2002) Redundancy Reduction and sustained Firing with Stochastic Depressing Synapses. J. Neuroscience 22:584–591

  17. Maldonado P. “El cerebro Humano, Desafio para el nuevo Milenio”. En: Nuevos Paradigmas a comienzos del tercer Milenio. Alvaro Fisher. Ed. El Mercurio/Aguilar (2004)

  18. Aylwin M. L., Diaz, E. and P.E. Maldonado. (2005) Simultaneous Single Unit Recording in the Mitral Cell Layer of the Rat Olfactory Bulb under Nasal and Tracheal Breathing. Biol. Res. 38(1):13-26.

  19. Aylwin M. L., and P.E. Maldonado. (2005) Una perspectiva sobre la Neurociencia en la investigación médica. En Huella y Presencia. Amanda Fuller ed. U de Chile. Eds.

  20. Egaña J.I., Aylwin M.L and P. E. Maldonado (2005) Odor Response Properties Of Adjacent Mitral/Tufted Cells In The Rat Olfactory Bulb. Neuroscience 134(3):1069-

  21. Valdés, J. L.; Maldonado, P.; Recabarren, M.; Fuentes, R.; Torrealba, F. (2006) The infralimbic cortical area commands the behavioral and vegetative arousal during appetitive behavior in the rat.. The European journal of neuroscience: 5 23:1352-64.

  22. Maldonado, P E; Babul, C M. Feb, (2007) Neuronal activity in the primary visual cortex of the cat freely viewing natural images. Neuroscience :4 144:1536-43.

  23. Maldonado, P E., Ossandon J.P. (2007) Time is of the essence: New approaches in neurophysiological research. In Nuevos enfoques de la cognición: redescubriendo la dinámica de la acción, la intención y la intersubjetividad. : Agustín Ibáñez, Diego Cosmelli. Eds. Ediciones Universidad Diego Portales. pp 53-70

  24. Maldonado, P E. (2008) What we see is how we are: new paradigms in visual research. Biol. Research 40(1) :439-450

  25. Maldonado, P E., Ossandon J.P. & Flores F.J. (2008) Attention and neurodynamical correlates of natural vision. From attention to goal-directed behavior: Neurodynamical and methodological and clinical trends. D. Cosmelli & F. Aboitiz Eds. Springer Verlag, Berlin pp : 67-82

  26. Delano P, Pavez E, Robles L, Maldonado PE. (2008) Stimulus-dependent oscillations and evoked potentials in chinchilla auditory cortex. J. Comp. Physiol. 194(8):693-700

  27. Pazienti A, Maldonado P, Diesmann M, Grün, S (2008) The effectiveness of systematic spike dithering depends on the precision of cortical synchronization. Brain. Res. 1225:39-46

  28. Maldonado, P E. (2008) Anatomia-Funcional de la percepción Visual. Tratado de Neurología Cognitiva y Neuropsicología. Editores: Andrea Slachevsky, Facundo Manes, Edith Labos, Patricio Fuentes. Editorial Akadia, BS, Argentina

  29. Donoso AM, Faúndes V, Falcón, F, Esparza P, Maldonado PE. (2008) Olfactory or auditory stimulation and their hedonic values differentially modulate visual working memory. Biol. Research 41: 379-387

  30. Fuentes R, Aguilar M, Aylwin ML, Maldonado PE, (2008) Neuronal activity of mitral-tufted cells in awake rats during passive and active odorant stimulation. J. of Neurophsyiol. J Neurophysiol. 100:422-430

  31. Maldonado PE, Babul C, Singer W, Rodriguez E, Berger D, Grün S (2008) Synchronization of neuronal responses in primary visual cortex of monkeys viewing natural images. J of Neurophsyiol. 100:1523-32

  32. Aylwin ML, Aguilar GA, Flores FJ, Maldonado PE. (2009) Odorant modulation of neuronal activity and local field potential in sensory deprived olfactory bulb. Neuroscience 162:1265-78.

  33. Delano PH, Elgueda D, Ramirez F, Robles L, Maldonado PE (2010) A Visual cue modulates the firing rate and latency of auditory-cortex neurons in the chinchilla. Journal of Physiology-Paris, 104:190-6.

  34. Ossandon JP, Helo A, Montefusco R, Maldonado PE. (2010) Superposition model predicts EEG occipital activity during free viewing of natural scenes. J. Neurosci. 30:4787-95.

  35. Ito H, Maldonado PE, Gray CM (2010) Dynamics of Stimulus-Evoked Spike Timing Correlations in the Cat Lateral Geniculate Nucleus. J Neurophysiol. 104:3276-92

  36. Ito J, Maldonado PE, Singer, W, Gruen S. (2011) Saccade-related modulations of neuronal excitability support synchrony of visually elicited spikes. Cerebral Cortex 21:2482-97.

  37. Devia, C, Maldonado, P. (2011) Phase-shift analysis on single-trial EEG signals and its correlation with behavior in a visual perceptual task. Neural Engineering (NER), 2011 5th International IEEE/EMBS Conference on Neural Engineering. DOI: 10.1109/NER.2011.5910640: P: 683-686

  38. Berger D, Pazienti A, Flores FJ, Nawrot MP, Maldonado PE, Grün S. (2012) Viewing strategy of Cebus monkeys during free exploration of natural images. Brain Res. 24:34-46.

  39. Manzur H, Alvarez J, Babul C, Maldonado PE (2013) Synchronization Across Sensory Cortical Areas by Electrical Microstimulation is Sufficient for Behavioral Discrimination. Cereb. Cortex. 23:2976-2986

  40. Ito J, Maldonado P, Grun S. (2013) Cross-frequency interaction of the eye-movement related LFP signals in V1 of freely viewing monkeys. doi: 10.3389/fnsys.2013.00001 Front Syst Neurosci.; 7:1-11

  41. Egaña JI, Devia C, Mayol R, Parrini J, Orellana G, Ruiz A, Maldonado PE (2013) Small saccades and image complexity during free viewing of natural images in schizophrenia of natural images in schizophrenia. doi: 10.3389/fpsyt.2013.00037 Front Psychiatry, 4:1-13

  42. Brunetti E, Maldonado PE, Aboitiz F. (2013) Phase synchronization of delta and theta oscillations increase during the detection of relevant lexical information. doi: 10.3389/fpsyg.2013.00308. Front Psycho., 4:1-13

  43. Montefusco-Siegmund R, Maldonado P, Devia C. (2013) Effects of Ocular Artifact Removal through ICA Decomposition on EEG Phase. International IEEE/EMBS Conference on Neural Engineering, NER2013, Article number 6696198, Pages 1374-1377 (Scopus).

  44. Loyola P, Brunetti E, Martinez G, Velasquez J, Maldonado, P (2014) “Leveraging Neurodata to Support Web User Behavior Analysis” in Wisdom Web of Things (W2T), SPRINGER

  45. Loyola P; Martinez G; Muñoz K; Velasquez J; Maldonado P; Couve A (2015) Combining Eye Tracking and Pupillary Dilation Analysis to Identify Website Key Objects. Neurocomputing 168: 179–189

  46. Mochizuki Y, Onaga T, Shimazaki H, Shimokawa T, Tsubo Y, Kimura R, Saiki A, Sakai Y, Isomura Y, Fujisawa S, Shibata K, Hirai D, Furuta T, Kaneko T, Takahashi S, Nakazono T, Ishino S, Sakurai Y, Kitsukawa T, Lee JW, Lee H, Jung MW, Babul C, Maldonado PE, Takahashi K, Arce-McShane FI, Ross CF, Sessle BJ, Hatsopoulos NG, Brochier T, Riehle A, Chorley P, Grün S, Nishijo H, Ichihara-Takeda S, Funahashi S, Shima K, Mushiake H, Yamane Y, Tamura H, Fujita I, Inaba N, Kawano K, Kurkin S, Fukushima K, Kurata K, Taira M, Tsutsui K, Ogawa T, Komatsu H, Koida K, Toyama K, Richmond BJ, Shinomoto S. (2016) Similarity in Neuronal Firing Regimes across Mammalian Species. J Neurosci. 36(21):5736-47. doi: 10.1523/JNEUROSCI.0230-16.2016.

  47. Vasquez-Rosati A, Brunetti EP, Cordero C, Maldonado PE. (2017) Pupillary Response to Negative Emotional Stimuli Is Differentially Affected in Meditation Practitioners. Front Hum Neurosci. 2017 May 3;11:209. doi: 10.3389/fnhum.2017.00209.

  48. Ito J, Yamane Y, Suzuki M, Maldonado P, Fujita I, Tamura H, Grün S. (2017) Switch from ambient to focal processing mode explains the dynamics of free viewing eye movements. Sci Rep. 2017 Apr 24;7(1):1082. doi: 10.1038/s41598-017-01076-w.

  49. Varas-Díaz G, Brunetti EP, Rivera-Lillo G, Maldonado PE. (2017) Patients with Chronic Spinal Cord Injury Exhibit Reduced Autonomic Modulation during an Emotion Recognition Task. Front Hum Neurosci. 2017 Feb 8;11:59. doi: 10.3389/fnhum.2017.00059. ECollection 2017.

  50. Villalobos C, Maldonado PE, Valdés JL. (2017) Asynchronous ripple oscillations between left and right hippocampi during slow-wave sleep. PLoS One. 2017 Feb 3;12(2):e0171304. doi: 10.1371/journal.pone.0171304. ECollection 2017.

  51. Vergara R, Moënne-Loccoz C & Maldonado PE. (2017) Cold-Blooded Attention: Finger Temperature Predicts Attentional Performance. Frontiers in Human Neuroscience, doi: 10.3389/fnhum.2017.00454.

  52. Fajnzylber V, González L, Maldonado P, Del Villar R, Yañez, R, Madariaga, S, Magdics, M. (2018) Augmented film narrative by use of non-photorealistic rendering. 2017 International Conference on 3D Immersion (IC3D), Brussels, 2017, pp. 1-8.
    doi: 10.1109/IC3D.2017.8251912

  53. Rojas-Líbano D, Wimmer Del Solar J, Aguilar-Rivera M, Montefusco-Siegmund R, Maldonado PE. (2018) Local cortical activity of distant brain areas can phase-lock to the olfactory bulb’s respiratory rhythm in the freely behaving rat. J Neurophysiol. 120:960-972. doi: 10.1152/jn.00088.2018.

  54. Burgos PI, Mariman JJ, Makeig S, Rivera-Lillo G, Maldonado PE. (2018) Visuomotor coordination and cortical connectivity of modular motor learning. Hum Brain Mapp. 39:3836-3853. doi: 10.1002/hbm.24215

  55. Montefusco-Siegmund R, Toro M, Maldonado PE, Aylwin ML. (2018) Unsupervised visual discrimination learning of complex stimuli: Accuracy, bias and generalization.
    Vision Res. Jul;148:37-48. doi: 10.1016/j.visres.2018.05.002.

  56. Galindo J, Contreras M, Maldonado P, Torrealba F, Lagos N, Valdés JL. (2018) Long-lasting, reversible and non-neurotoxic inactivation of hippocampus activity induced by neosaxitoxin. J Neurosci Methods. 308:197-204. doi: 10.1016/j.jneumeth.2018.08.013.

  57. Mariman JJ, Burgos P, Maldonado PE. (2018) Parallel learning processes of a visuomotor adaptation task in a changing environment. Eur J Neurosci. 2019 Jan;49(1):106-119. doi: 10.1111/ejn.14258. Epub 2018 Nov 26.

  58. Rivera-Lillo G, Rojas D, Burgos P, Egaña JI, Chennu S, Maldonado PE. (2018) Reduced delta-band modulation underlies the loss of P300 responses in disorders of consciousness. Clin Neurophysiol. 2018 Nov 9;129(12):2613-2622. doi: 10.1016/j.clinph.2018.09.104.

  59. Astudillo C, Muñoz K, Maldonado PE. (2018) Emotional Content Modulates Attentional Visual Orientation During Free Viewing of Natural Images. Front Hum Neurosci. 2018 Nov 15;12:459. doi: 10.3389/fnhum.2018.00459. eCollection 2018.

  60. Gajardo AIJ, Madariaga S, Maldonado PE. (2018) Autonomic nervous system assessment by pupillary response as a potential biomarker for cardiovascular risk: A pilot study. J Clin Neurosci. 2018 Nov 15. pii: S0967-5868(18)31221-9. doi: 10.1016/j.jocn.2018.11.015.

  61. Maldonado, P E. (2018) Anatomia-Funcional de la percepción Visual. Tratado de Neurología Cognitiva y Neuropsicología. 2da Edicion. Editores: Andrea Slachevsky, Facundo Manes, Edith Labos, Patricio Fuentes. Editorial Akadia, BS, Argentina

  62. Vergara RC, Moënne-Loccoz C, Ávalos C, Egaña J, Maldonado PE. (2019) Finger Temperature: A Psychophysiological Assessment of the Attentional State. Front Hum Neurosci. Mar 13;13:66. doi: 10.3389/fnhum.2019.00066. eCollection 2019.

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