Patricio Alejandro Olguín Aguilera

Seleccionadas

Desde ORCID

• Differences and contributors to global cognitive performance in the underrepresented Latinx Parkinson’s disease population

  Anis, S., Chaparro-Solano, H. M., Peixoto Leal, T., Sperling, S. A., Sonneborn, C., Callegari Piccinin, C., Inca-Martinez, M., Cornejo-Olivas, M., Illanes-Manrique, M., Chana-Cuevas, P., Safie Awad, P., Jimena Hernández-Medrano, A., Cervantes-Arriaga, A., F. S. Schuh, A., R. M. Rieder, C., Braga-Neto, P., Andrei da Silva Sena, A., Lopes Santos-Lobato, B., M. Gatto, E., J. Alvarado, G., L. Avila, C., Tumas, V. & et al.

  The Clinical Neuropsychologist, 39, 1905-1925 doi:10.1080/13854046.2025.2450020

• EEFSEC deficiency: A selenopathy with early-onset neurodegeneration

  Laugwitz, L., Buchert, R., Olguín, P., Estiar, M. A., Atanasova, M., Jr., W. M., Enssle, J., Marsden, B., Avilés, J., González-Gutiérrez, A., Candia, N., Fabiano, M., Morlot, S., Peralta, S., Groh, A., Schillinger, C., Kuehn, C., Sofan, L., Sturm, M., Bender, B., Tomaselli, P. J., Diebold, U. & et al.

  The American Journal of Human Genetics, 112, 168-180 doi:10.1016/j.ajhg.2024.12.001

• Genetic Architecture of the Thermal Tolerance Landscape in <i>Drosophila melanogaster</i>

  Soto, J., Pinilla, F., Olguín, P. & Castañeda, L. E.

  Molecular Ecology, 34 doi:10.1111/mec.17697

• Sex differences in the diagnosis latency of Parkinson's disease in Latin America

  Ramchandra, J., Inca-Martinez, M., Leal, T. P., Chaparro-Solano, H. M., Salim, A., Gatto, E. M., Rojas, N. G., Da Prat, G., Micheli, F., Santos-Lobato, B. L., Cardoso, F. E., Camargos, S., Letro, G. H., Braga-Neto, P., Peixoto, V. M. T., Schuh, A. F., Tumas, V., Brito, M. M., Borges, V., Candeias da Silva, C., Ferraz, H. B., Chana-Cuevas, P. & et al.

  Parkinsonism &amp; Related Disorders, 134, 107344 doi:10.1016/j.parkreldis.2025.107344

• The LRRK2 p.L1795F variant causes Parkinson’s disease in the European population

  Lange, L. M., Levine, K., Fox, S. H., Marras, C., Ahmed, N., Kuznetsov, N., Vitale, D., Iwaki, H., Lohmann, K., Marsili, L., Espay, A. J., Bauer, P., Beetz, C., Martin, J., Factor, S. A., Higginbotham, L. A., Chen, H., Leonard, H., Nalls, M. A., Mencacci, N. E., Morris, H. R., Singleton, A. B. & et al.

  npj Parkinson's Disease, 11 doi:10.1038/s41531-025-00896-2

• <i>GBA</i> 1 rs3115534 Is Associated with <scp>REM</scp> Sleep Behavior Disorder in Parkinson's Disease in Nigerians

  Ojo, O. O., Bandres‐Ciga, S., Makarious, M. B., Crea, P. W., Hernandez, D. G., Houlden, H., Rizig, M., Singleton, A. B., Noyce, A. J., Nalls, M. A., Blauwendraat, C., Okubadejo, N. U. & the Nigeria Parkinson's Disease Research Network and the Global Parkinson's Genetics Program (GP2)

  Movement Disorders, 39, 728-733 doi:10.1002/mds.29753

• Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease

  Kim, J. J., Vitale, D., Otani, D. V., Lian, M. M., Heilbron, K., the 23andMe Research Team, Aslibekyan, S., Auton, A., Babalola, E., Bell, R. K., Bielenberg, J., Bryc, K., Bullis, E., Cannon, P., Coker, D., Partida, G. C., Dhamija, D., Das, S., Elson, S. L., Eriksson, N., Filshtein, T., Fitch, A. & et al.

  Nature Genetics, 56, 27-36 doi:10.1038/s41588-023-01584-8

• Author Correction: Elucidating causative gene variants in hereditary Parkinson’s disease in the Global Parkinson’s Genetics Program (GP2)

  Lange, L. M., Avenali, M., Ellis, M., Illarionova, A., Keller Sarmiento, I. J., Tan, A. H., Madoev, H., Galandra, C., Junker, J., Roopnarain, K., Solle, J., Wegel, C., Fang, Z. H., Heutink, P., Kumar, K. R., Lim, S. Y., Valente, E. M., Nalls, M., Blauwendraat, C., Singleton, A., Mencacci, N., Lohmann, K. & et al.

  npj Parkinson's Disease, 9 doi:10.1038/s41531-023-00560-7

• Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2)

  Towns, C., Richer, M., Jasaityte, S., Stafford, E. J., Joubert, J., Antar, T., Martinez-Carrasco, A., Makarious, M. B., Casey, B., Vitale, D., Levine, K., Leonard, H., Pantazis, C. B., Screven, L. A., Hernandez, D. G., Wegel, C. E., Solle, J., Nalls, M. A., Blauwendraat, C., Singleton, A. B., Tan, M. M. X., Iwaki, H. & et al.

  npj Parkinson's Disease, 9 doi:10.1038/s41531-023-00533-w

• Early-life nutrition interacts with developmental genes to shape the brain and sleep behavior in <i>Drosophila melanogaster</i>

  Olivares, G. H., Núñez-Villegas, F., Candia, N., Oróstica, K., González-Ramírez, M. C., Vega-Macaya, F., Zúñiga, N., Molina, C., Oliva, C., Mackay, T. F. C., Verdugo, R. A. & Olguín, P.

  Sleep, 46 doi:10.1093/sleep/zsad016

• Editorial: The role of early-life nutrition and metabolism in brain development and adult behavior

  Olivares, G. H. & Olguín, P.

  Frontiers in Neuroscience, 17 doi:10.3389/fnins.2023.1308183

• Identification of atlastin genetic modifiers in a model of hereditary spastic paraplegia in Drosophila

  Candia, N., Ibacache, A., Medina-Yáñez, I., Olivares, G. H., Ramírez, M., Vega-Macaya, F., Couve, A., Sierralta, J. & Olguín, P.

  Human Genetics, 142, 1303-1315 doi:10.1007/s00439-023-02577-7

• Low-nutrient diet in <i>Drosophila</i> larvae stage causes enhancement in dopamine modulation in adult brain due epigenetic imprinting

  Zúñiga-Hernández, J. M., Olivares, G. H., Olguín, P. & Glavic, A.

  Open Biology, 13 doi:10.1098/rsob.230049

• Developmentally regulated alternate 3′ end cleavage of nascent transcripts controls dynamic changes in protein expression in an adult stem cell lineage

  Berry, C. W., Olivares, G. H., Gallicchio, L., Ramaswami, G., Glavic, A., Olguín, P., Li, J. B. & Fuller, M. T.

  Genes &amp; Development, 36, 916-935 doi:10.1101/gad.349689.122

• Genetic Background Matters: Population-Based Studies in Model Organisms for Translational Research

  Olguín, V., Durán, A., Las Heras, M., Rubilar, J. C., Cubillos, F. A., Olguín, P. & Klein, A. D.

  International Journal of Molecular Sciences, 23, 7570 doi:10.3390/ijms23147570

• The conserved Pelado/ZSWIM8 protein regulates actin dynamics by promoting linear actin filament polymerization

  Molina-Pelayo, C., Olguin, P., Mlodzik, M. & Glavic, A.

  Life Science Alliance, 5, e202201484 doi:10.26508/lsa.202201484

• Underrepresented Populations in Parkinson's Genetics Research: Current Landscape and Future Directions

  Schumacher‐Schuh, A. F., Bieger, A., Okunoye, O., Mok, K. Y., Lim, S., Bardien, S., Ahmad‐Annuar, A., Santos‐Lobato, B. L., Strelow, M. Z., Salama, M., Rao, S. C., Zewde, Y. Z., Dindayal, S., Azar, J., Prashanth, L. K., Rajan, R., Noyce, A. J., Okubadejo, N., Rizig, M., Lesage, S., Mata, I. F. & Global Parkinson's Genetics Program (GP2)

  Movement Disorders, 37, 1593-1604 doi:10.1002/mds.29126

• Phosphatidic acid increases Notch signalling by affecting Sanpodo trafficking during Drosophila sensory organ development

  Medina-Yáñez, I., Olivares, G. H., Vega-Macaya, F., Mlodzik, M. & Olguín, P.

  Scientific Reports, 10 doi:10.1038/s41598-020-78831-z

• Modeling Parkinson’s Disease Heterogeneity to Accelerate Precision Medicine

  Olivares, G. H., Olguín, P. & Klein, A. D.

  Trends in Molecular Medicine, 25, 1052-1055 doi:10.1016/j.molmed.2019.09.004

• Jitterbug/Filamin and Myosin-II form a complex in tendon cells required to maintain epithelial shape and polarity during musculoskeletal system development

  Manieu, C., Olivares, G. H., Vega-Macaya, F., Valdivia, M. & Olguín, P.

  Mechanisms of Development, 154, 309-314 doi:10.1016/j.mod.2018.09.002

• Mechanical Control of Myotendinous Junction Formation and Tendon Differentiation during Development

  Valdivia, M., Vega-Macaya, F. & Olguín, P.

  Frontiers in Cell and Developmental Biology, 5 doi:10.3389/fcell.2017.00026

• Establishment of the Muscle–Tendon Junction During Thorax Morphogenesis in <i>Drosophila</i> Requires the Rho-Kinase

  Vega-Macaya, F., Manieu, C., Valdivia, M., Mlodzik, M. & Olguín, P.

  Genetics, 204, 1139-1149 doi:10.1534/genetics.116.189548

• Presynaptic DLG regulates synaptic function through the localization of voltage-activated Ca2+ Channels

  Astorga, C., Jorquera, R. A., Ramírez, M., Kohler, A., López, E., Delgado, R., Córdova, A., Olguín, P. & Sierralta, J.

  Scientific Reports, 6 doi:10.1038/srep32132

• Hindsight regulates photoreceptor axon targeting through transcriptional control of <i>jitterbug/Filamin</i> and multiple genes involved in axon guidance in <scp><i>D</i></scp>rosophila

  Oliva, C., Molina‐Fernandez, C., Maureira, M., Candia, N., López, E., Hassan, B., Aerts, S., Cánovas, J., Olguín, P. & Sierralta, J.

  Developmental Neurobiology, 75, 1018-1032 doi:10.1002/dneu.22271

• <i>Drosophila</i>p53-related protein kinase is required for PI3K/TOR pathway-dependent growth

  Ibar, C., Cataldo, V. F., Vásquez-Doorman, C., Olguín, P. & Glavic, Á.

  Development, 140, 1282-1291 doi:10.1242/dev.086918

• <i>Drosophila</i> CK1-γ, <i>gilgamesh</i>, controls PCP-mediated morphogenesis through regulation of vesicle trafficking

  Gault, W. J., Olguin, P., Weber, U. & Mlodzik, M.

  Journal of Cell Biology, 196, 605-621 doi:10.1083/jcb.201107137

• Novel Regulators of Planar Cell Polarity: A Genetic Analysis in <i>Drosophila</i>

  Weber, U., Gault, W. J., Olguin, P., Serysheva, E. & Mlodzik, M.

  Genetics, 191, 145-162 doi:10.1534/genetics.111.137190

• Intertissue Mechanical Stress Affects Frizzled-Mediated Planar Cell Polarity in the Drosophila Notum Epidermis

  Olguín, P., Glavic, A. & Mlodzik, M.

  Current Biology, 21, 236-242 doi:10.1016/j.cub.2011.01.001

• A New Spin on Planar Cell Polarity

  Olguin, P. & Mlodzik, M.

  Cell, 142, 674-676 doi:10.1016/j.cell.2010.08.025

• Temporal and spatial expression of Drosophila DLGS97 during neural development

  Albornoz, V., Mendoza-Topaz, C., Oliva, C., Tello, J., Olguín, P. & Sierralta, J.

  Gene Expression Patterns, 8, 443-451 doi:10.1016/j.gep.2008.04.001

• Erratum: Novel isoforms of dlg are fundamental for neuronal development in drosophila (Journal of Neuroscience (2003) (2093-2101))

  Journal of Neuroscienceenlace

• Developmental regulation of the expression of sodium currents in Xenopus primary neurons

  OLGUÍN, P., ARMISEN, R. & KUKULJAN, M.

  Biological Research, 39 doi:10.4067/s0716-97602006000300010

• RE-1 Silencer of Transcription/Neural Restrictive Silencer Factor Modulates Ectodermal Patterning during<i>Xenopus</i>Development

  Olguín, P., Oteíza, P., Gamboa, E., Gómez-Skármeta, J. L. & Kukuljan, M.

  The Journal of Neuroscience, 26, 2820-2829 doi:10.1523/jneurosci.5037-05.2006

• Novel Isoforms of Dlg Are Fundamental for Neuronal Development in<i>Drosophila</i>

  Mendoza, C., Olguı́n, P., Lafferte, G., Thomas, U., Ebitsch, S., Gundelfinger, E. D., Kukuljan, M. & Sierralta, J.

  The Journal of Neuroscience, 23, 2093-2101 doi:10.1523/jneurosci.23-06-02093.2003

• Selective Regulation of xSlo Splice Variants During<i>Xenopus</i>Embryogenesis

  Kukuljan, M., Taylor, A., Chouinard, H., Olguín, P., Rojas, C. V. & Ribera, A. B.

  Journal of Neurophysiology, 90, 3352-3360 doi:10.1152/jn.00398.2003

• Repressor Element-1 Silencing Transcription/Neuron-Restrictive Silencer Factor Is Required for Neural Sodium Channel Expression during Development of<i>Xenopus</i>

  Armisén, R., Fuentes, R., Olguı́n, P., Cabrejos, M. E. & Kukuljan, M.

  The Journal of Neuroscience, 22, 8347-8351 doi:10.1523/jneurosci.22-19-08347.2002