Gonzalo Andrés Farías Gontupil

Desde ORCID

• A Clinically Oriented Serious Game for Executive Dysfunction: Development and Usability in Real-Life Contexts (Preprint)

  Olivares, D., Martínez-Pernía, D., Olavarría, L., Cerda, M., Montenegro, D., Nieto, R., Farías, G. & Slachevsky, A.

  doi:10.2196/preprints.94860

• Executive Dysfunction—A Serious Game for Assessment in Real-Life Contexts: Development and Cross-Sectional Usability Study

  Olivares, D., Martínez-Pernía, D., Olavarría, L., Cerda, M., Montenegro, D., Ramírez, C., Nieto, R., Farías, G. & Slachevsky, A.

  JMIR Serious Games, 14, e94860-e94860 doi:10.2196/94860

• The impact of social isolation and perceived loneliness in older adults: a cross-sectional descriptive Chilean study

  Gierke, C., Navarro, C. F., Martinez, M., Delgado, C., Diaz-Gierke, W., Diaz, R. & Farias, G.

  Frontiers in Psychology, 16 doi:10.3389/fpsyg.2025.1683933

• White matter hyperintensities are associated with locus coeruleus atrophy and astrocytic β ₂ ‐adrenergic receptor expression

  Vidal, V., Farías, G., Delgado, C., Delano, P. H., Vergara, R. C., Orellana, P., Ossandón, T., Crossley, N. A., Gonzalez‐Campo, C., Naismith, S. L., Gonzalez‐Gomez, R., Coronel‐Oliveros, C., Ibáñez, A., Wainstein, G., Sanders, R. D., Shine, J. M. & Medel, V.

  Alzheimer's & Dementia, 22 doi:10.1002/alz.71583

• Cochlear dysfunction as an early biomarker of cognitive decline in normal hearing and mild hearing loss

  Medel, V., Delano, P. H., Belkhiria, C., Leiva, A., De Gatica, C., Vidal, V., Navarro, C. F., Martín, S. S., Martínez, M., Gierke, C., García, X., Cerda, M., Vergara, R., Delgado, C. & Farías, G. A.

  Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 16 doi:10.1002/dad2.12467

• Exploring Levodopa-induced dyskinesia in Latin American Parkinson`s disease patients: Insights from the large-PD Consortium

  Chaparro-Solano, H., Inca-Martinez, M., Peixoto-Leal, T., Martinez-Ramirez, D., González-González, M., Rodriguez-Violante, M., Hernández-Medrano, A., Rentería, M., Alcauter, S., Olguin, P., Flores, A. C., de la Cerda, A., Farías, G., Nuñez, J., Chana-Cuevas, P., Saffie, P., Gatto, E., Rojas, N. G., Da Prat, G., Micheli, F., Marchetti, C., Franchello, E. & et al.

  Parkinsonism & Related Disorders, 122, 106121 doi:10.1016/j.parkreldis.2024.106121

• Exploring Neuroprotection against Radiation-Induced Brain Injury: A Review of Key Compounds

  González-Johnson, L., Fariña, A., Farías, G., Zomosa, G., Pinilla-González, V. & Rojas-Solé, C.

  NeuroSci, 5, 462-484 doi:10.3390/neurosci5040034

• Alzheimer’s Disease as a potential diabetes type III: Pilot Study of comorbidities related to AD

  González, A., Camila, C., Maccioni, R. B., Farías, G. & Fuentes, P.

  Alzheimer's & Dementia, 19 doi:10.1002/alz.078278

• Biomarkers for dementia in Latin American countries: Gaps and opportunities

  Parra, M. A., Orellana, P., Leon, T., Victoria, C. G., Henriquez, F., Gomez, R., Avalos, C., Damian, A., Slachevsky, A., Ibañez, A., Zetterberg, H., Tijms, B. M., Yokoyama, J. S., Piña‐Escudero, S. D., Cochran, J. N., Matallana, D. L., Acosta, D., Allegri, R., Arias‐Suárez, B. P., Barra, B., Behrens, M. I., Brucki, S. M. D. & et al.

  Alzheimer's & Dementia, 19, 721-735 doi:10.1002/alz.12757

• The limitations and challenges in the assessment of executive dysfunction associated with real-world functioning: The opportunity of serious games

  Martínez-Pernía, D., Olavarría, L., Fernández-Manjón, B., Cabello, V., Henríquez, F., Robert, P., Alvarado, L., Barría, S., Antivilo, A., Velasquez, J., Cerda, M., Farías, G., Torralva, T., Ibáñez, A., Parra, M. A., Gilbert, S. & Slachevsky, A.

  Applied Neuropsychology: Adult, 32, 557-573 doi:10.1080/23279095.2023.2174438

• Multi-feature computational framework for combined signatures of dementia in underrepresented settings

  Moguilner, S., Birba, A., Fittipaldi, S., Gonzalez-Campo, C., Tagliazucchi, E., Reyes, P., Matallana, D., Parra, M. A., Slachevsky, A., Farías, G., Cruzat, J., García, A., Eyre, H. A., La Joie, R., Rabinovici, G., Whelan, R. & Ibáñez, A.

  Journal of Neural Engineering, 19, 046048 doi:10.1088/1741-2552/ac87d0

• Estrategias no farmacológicas en personas con Demencia Avanzada: reporte de un caso.

  Acevedo P., F., Delgado Derio, C. & Farías, G.

  Revista chilena de neuro-psiquiatría, 59, 368-374 doi:10.4067/s0717-92272021000400368

• Interventional Study to Evaluate the Clinical Effects and Safety of the Nutraceutical Compound BrainUp-10® in a Cohort of Patients with Alzheimer’s Disease: A Multicenter, Randomized, Double-Blind, and Placebo-Controlled Trial

  Guzman-Martinez, L., Farías, G. A., Tapia, J. P., Sánchez, M. P., Fuentes, P., Gloger, S. & Maccioni, R. B.

  Journal of Alzheimer's Disease, 81, 1231-1241 doi:10.3233/jad-201501

• New Frontiers in the Prevention, Diagnosis, and Treatment of Alzheimer’s Disease

  Guzman-Martinez, L., Calfío, C., Farias, G. A., Vilches, C., Prieto, R. & Maccioni, R. B.

  Journal of Alzheimer's Disease, 82, S51-S63 doi:10.3233/jad-201059

• Association of Vitamin D Receptor Polymorphisms with Amyloid-β Transporters Expression and Risk of Mild Cognitive Impairment in a Chilean Cohort

  Arévalo, N. B., Castillo-Godoy, D. P., Espinoza-Fuenzalida, I., Rogers, N. K., Farias, G., Delgado, C., Henriquez, M., Herrera, L., Behrens, M. I. & SanMartín, C. D.

  Journal of Alzheimer's Disease, 82, S283-S297 doi:10.3233/jad-201031

• Dementia in Latin America: Paving the way toward a regional action plan

  Parra, M. A., Baez, S., Sedeño, L., Gonzalez Campo, C., Santamaría‐García, H., Aprahamian, I., Bertolucci, P. H., Bustin, J., Camargos Bicalho, M. A., Cano‐Gutierrez, C., Caramelli, P., Chaves, M. L. F., Cogram, P., Beber, B. C., Court, F. A., de Souza, L. C., Custodio, N., Damian, A., de la Cruz, M., Diehl Rodriguez, R., Brucki, S. M. D., Fajersztajn, L. & et al.

  Alzheimer's & Dementia, 17, 295-313 doi:10.1002/alz.12202

• Biomarkers for Alzheimer’s Disease

  Guzman-Martinez, L., Maccioni, R. B., Farías, G. A., Fuentes, P. & Navarrete, L. P.

  Current Alzheimer Research, 16, 518-528 doi:10.2174/1567205016666190517121140

• Prospective Assessment of No Evidence of Disease Activity-4 Status in Early Disease Stages of Multiple Sclerosis in Routine Clinical Practice

  Guevara, C., Garrido, C., Martinez, M., Farias, G. A., Orellana, P., Soruco, W., Alarcón, P., Diaz, V., Silva, C., Kempton, M. J., Barker, G. & de Grazia, J.

  Frontiers in Neurology, 10 doi:10.3389/fneur.2019.00788

• The Alz-tau Biomarker for Alzheimer’s Disease: Study in a Caucasian Population

  Guzmán-Martínez, L., Tapia, J. P., Farías, G. A., González, A., Estrella, M. & Maccioni, R. B.

  Journal of Alzheimer’s Disease, 67, 1181-1186 doi:10.3233/jad-180637

• Encephalitis Associated to Metabotropic Glutamate Receptor 5 (mGluR5) Antibodies in Cerebrospinal Fluid

  Guevara, C., Farias, G., Silva-Rosas, C., Alarcon, P., Abudinen, G., Espinoza, J., Caro, A., Angus-Leppan, H. & de Grazia, J.

  Frontiers in Immunology, 9 doi:10.3389/fimmu.2018.02568

• The Emergency of Nutraceutical Compounds in the Preventive Medicine Scenario. Potential for Treatment of Alzheimer's Disease and Other Chronic Disorders

  Andrade, V., Guzman-Martinez, L., Cortes, N., Gonzalez, A., Farias, G. & Maccioni, R. B.

  Journal of Alzheimer’s Disease & Parkinsonism, 08 doi:10.4172/2161-0460.1000456

• NOTCH 1 Mutation in a Patient with Spontaneous and Recurrent Dissections of Extracranial Arteries

  Guevara, C., Farias, G., Bulatova, K., Alarcón, P., Soruco, W., Robles, C. & Morales, M.

  Frontiers in Neurology, 8 doi:10.3389/fneur.2017.00245

• Retrospective diagnosis of Parkinsonian syndromes using whole-brain atrophy rates

  Frontiers in Aging Neuroscience doi:10.3389/fnagi.2017.00099/full

• Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer’s Disease

  Slachevsky, A., Guzmán-Martínez, L., Delgado, C., Reyes, P., Farías, G. A., Muñoz-Neira, C., Bravo, E., Farías, M., Flores, P., Garrido, C., Becker, J. T., López, O. L. & Maccioni, R. B.

  Journal of Alzheimer's Disease, 55, 1595-1603 doi:10.3233/jad-160652

• Neuroinflammation in the pathogenesis of Alzheimer’s disease. A rational framework for the search of novel therapeutic approaches

  Morales, I., Guzmán-Martínez, L., Cerda-Troncoso, C., Farías, G. A. & Maccioni, R. B.

  Frontiers in Cellular Neuroscience, 8 doi:10.3389/fncel.2014.00112

• Nutraceuticals: A Novel Concept in Prevention and Treatment of Alzheimer's Disease and Related Disorders

  Farías, G. A., Guzmán-Martínez, L., Delgado, C. & Maccioni, R. B.

  Journal of Alzheimer's Disease, 42, 357-367 doi:10.3233/jad-132741

• Tau Oligomers as Potential Targets for Alzheimer’s Diagnosis and Novel Drugs

  Guzmán-Martinez, L., Farías, G. A. & Maccioni, R. B.

  Frontiers in Neurology, 4 doi:10.3389/fneur.2013.00167

• Can Nutraceuticals Prevent Alzheimer's Disease? Potential Therapeutic Role of a Formulation Containing Shilajit and Complex B Vitamins

  Carrasco-Gallardo, C., Farías, G. A., Fuentes, P., Crespo, F. & Maccioni, R. B.

  Archives of Medical Research, 43, 699-704 doi:10.1016/j.arcmed.2012.10.010

• Emerging Noninvasive Biomarkers for Early Detection of Alzheimer's Disease

  Guzmán-Martínez, L., Farías, G. A. & Maccioni, R. B.

  Archives of Medical Research, 43, 663-666 doi:10.1016/j.arcmed.2012.10.013

• Platelet Tau Pattern Correlates with Cognitive Status in Alzheimer's Disease

  Farías, G., Pérez, P., Slachevsky, A. & Maccioni, R. B.

  Journal of Alzheimer's Disease, 31, 65-69 doi:10.3233/jad-2012-120304

• Human Platelets Tau: A Potential Peripheral Marker for Alzheimer's Disease

  Neumann, K., Farías, G., Slachevsky, A., Perez, P. & Maccioni, R. B.

  Journal of Alzheimer's Disease, 25, 103-109 doi:10.3233/jad-2011-101641

• Mechanisms of Tau Self-Aggregation and Neurotoxicity

  Farias, G., Cornejo, A., Jimenez, J., Guzman, L. & B. Maccioni, R.

  Current Alzheimer Research, 8, 608-614 doi:10.2174/156720511796717258

• La neuroinflamación como factor detonante del desarrollo de la enfermedad de Alzheimer

  Morales G, I., Farías G, G. & Maccioni B, R. B.

  Revista chilena de neuro-psiquiatría, 48 doi:10.4067/s0717-92272010000200007

• Neuroimmunomodulation in the Pathogenesis of Alzheimer’s Disease

  Morales, I., Farías, G. & Maccioni, R. B.

  Neuroimmunomodulation, 17, 202-204 doi:10.1159/000258724

• P3‐198: Tau in platelets as a potential biological marker for Alzheimer's disease

  Farias, G., Neurmann, K., Slachevsky, A., Perez, P. & Maccioni, R.

  Alzheimer's & Dementia, 6 doi:10.1016/j.jalz.2010.05.1696

• The Revitalized Tau Hypothesis on Alzheimer's Disease

  Maccioni, R. B., Farías, G., Morales, I. & Navarrete, L.

  Archives of Medical Research, 41, 226-231 doi:10.1016/j.arcmed.2010.03.007

• Insulin Resistance and Alzheimers Disease: Molecular Links & Clinical Implications

  Neumann, K., Rojo, L., Navarrete, L., Farias, G., Reyes, P. & Maccioni, R.

  Current Alzheimer Research, 5, 438-447 doi:10.2174/156720508785908919

• Comparison of cardiac output measurement in critical patients using transesophageal Doppler or thermodilution. A preliminary report,Determinación y análisis comparativo de gasto cardíaco en enfermos críticos mediante Doppler transesofágico y termodilución en bolos. Experiencia preliminar

  Revista Medica de Chileenlace

• Determinación y análisis comparativo de gasto cardíaco en enfermos críticos mediante Doppler transesofágico y termodilución en bolos: Experiencia preliminar

  Andresen H, M., Henríquez V, M., Mercado F, M., Farías G, G., Castillo S, C., Benítez G, C. & Dougnac L, A.

  Revista médica de Chile, 133 doi:10.4067/s0034-98872005000700002

• Uso de plasmaféresis en unidades de pacientes críticos

  Benítez G, C., Andresen, M., Farías G, G., Castillo S, C., Henríquez V, M. & Pereira, J.

  Revista médica de Chile, 133 doi:10.4067/s0034-98872005001200005

• Development of an instrument to assess the severity of community acquired pneumonia among hospitalized patients,Diseño de un índice pronóstico clínico para el manejo de la neumonía del adulto adquirida en la comunidad

  Revista Medica de Chileenlace

• Diseño de un índice pronóstico clínico para el manejo de la neumonía del adulto adquirida en la comunidad

  Saldías P, F., Farías G, G., Villarroel D, L., Valdivia C, G., Mardónez U, J. M. & Díaz F, A.

  Revista médica de Chile, 132 doi:10.4067/s0034-98872004000900003

• Clinical usefulness of blood cultures in hospitalized patients with community-acquired pneumonia,Utilidad clínica de los hemocultivos en pacientes hospitalizados por neumonía adquirida en la comunidad

  Revista Medica de Chileenlace

• Neumonía adquirida en la comunidad en el adulto hospitalizado: Cuadro clínico y factores pronósticos

  Saldías P, F., Mardónez U, J. M., Marchesse R, M., Viviani G, P., Farías G, G. & Díaz F, A.

  Revista médica de Chile, 130 doi:10.4067/s0034-98872002001200007

• Prognostic factors and outcome of community-acquired pneumonia in hospitalized adult patients,Neumonía adquirida en la comunidad en el adulto hospitalizado. Cuadro clínico y factores pronósticos

  Revista Medica de Chileenlace

• Utilidad clínica de los hemocultivos en pacientes hospitalizados por neumonía adquirida en la comunidad

  Díaz F, A., Calvo A, M., O'Brien S, A., Farías G, G., Mardónez U, J. M. & Saldías P, F.

  Revista médica de Chile, 130 doi:10.4067/s0034-98872002000900005