Académico(a):

Patricio Alejandro Olguin Aguilera

patricioolguin@med.uchile.cl

Formación:

  • Doctor de la Universidad de Chile,2007
  • Bioquímico de la Universidad de Chile,2001

Categoría académica:

  • Profesor asistente Instituto de Ciencias Biomédicas ,Facultad de Medicina Universidad de Chile.
  • Profesor Asistente Departamento de Neurociencias ,Facultad de Medicina Universidad de Chile .

Linea de Investigación 

  • Therole of jitterbug/Filamin in celular mechanoresponse to tissue interaction during development.
  • Anillo de Drosophila en Adaptaciones al Estrés Nutricional en el Desarrollo (DRiDANS).
  • Red de Colaboración Neurosur: Un Cerebro para América Latina

Publicaciones :

  • Jitterbug/Filamin and Myosin-II form a complex in tendon cells required to maintain epithelial shape and polarity during musculoskeletal system development,MECHANISMS OF DEVELOPMENT 2018
  • Mechanical Control of Myotendinous Junction Formation and Tendon Differentiation during Development,FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2017.
  • Presynaptic DLG regulates synaptic function through the localization of voltage-activated Ca2+ Channels,SCIENTIFIC REPORTS 2016.
  • Establishment of the Muscle-Tendon Junction During Thorax Morphogenesis in Drosophila Requires the Rho-Kinase,GENETICS 2016.
  • Hindsight regulates photoreceptor axon targeting through transcriptional control of jitterbug/Filamin and multiple genes involved in axon guidance in Drosophila,DEVELOPMENTAL NEUROBIOLOGY 2015.
  • Hindsight regulates photoreceptor axon targeting through transcriptional control of jitterbug/Filamin and multiple genes involved in actin regulation and axon targeting in Drosophila,MOLECULAR BIOLOGY OF THE CELL 2015.
  • Drosophila p53-related protein kinase is required for PI3K/TOR pathway-dependent growth,DEVELOPMENT 2013.
  • Jitterbug(jbug)/Filamin and Protein Tyrosine Phosphatase 69D (PTP69D) are required for tendon cell orientation and axon targeting in Drosophila,MOLECULAR BIOLOGY OF THE CELL 2012.
  • Identification of HNT targets in the eye.
  • Intertissue Mechanical Stress Affects Frizzled-Mediated Planar Cell Polarity in the Drosophila Notum Epidermis,CURRENT BIOLOGY 2011.
  • Temporal and spatial expression of Drosophila DLGS97 during neural development,GENE EXPRESSION PATTERNS 2008.
  • Developmental regulation of the expression of sodium currents in Xenopus primary neurons,Developmental regulation of the expression of sodium currents in Xenopus primary neurons 2006.
  • RE-1 silencer of transcription/neural restrictive silencer factor modulates ectodermal patterning during Xenopus development,JOURNAL OF NEUROSCIENCE 2006.

 

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