Académico(a):

Jose Luis Valdés Guerrero

jlvaldes@med.uchile.cl

Formación:

  • Licenciado en Ciencias Biológicas , Universidad Católica 1999.
  • Doctorado, Universidad de Chile 2005.

 

Categoría académica:

  • Profesor Asistente Departamento de Neurociencias Facultad de Medicina

          Lineas de Investigación :

  • Test de navegación virtual detecta de forma rápida y precisa el deterioro cognitivo inicial en personas mayores
  • The precise timing of motor modulations as a mechanism for active sensing in the visual system
  • Defective calcium/redox signaling and anomalous electrical brain activity in rats injected with amyloid beta oligomers: functional and behavioral correlates with Alzheimer´s patients
  • Role of hippocampal histaminergic activity during acquisition and consolidation of memory
  • Mesenchymal stem cells-secretome: Protection in neonatal hypoxia-reoxygenation. Mechanisms and translational studies
  • Red de Colaboración Neurosur: Un Cerebro para América Latina

 

Publicaciones :

  • Timing Is of the Essence: Improvement in Perception During Active Sensing,FRONTIERS IN BEHAVIORAL NEUROSCIENCE 2019.
  • Long-lasting, reversible and non-neurotoxic inactivation of hippocampus activity induced by neosaxitoxin,JOURNAL OF NEUROSCIENCE METHODS 2018.
  • Targeting Sentinel Proteins and Extrasynaptic Glutamate Receptors: a Therapeutic Strategy for Preventing the Effects Elicited by Perinatal Asphyxia?,NEUROTOXICITY RESEARCH 2018.
  • Calcium Release Mediated by Redox-Sensitive RyR2 Channels Has a Central Role in Hippocampal Structural Plasticity and Spatial Memory,ANTIOXIDANTS & REDOX SIGNALING 2018.
  • N-Acetylcysteine Prevents the Spatial Memory Deficits and the Redox-Dependent RyR2 Decrease Displayed by an Alzheimer’s Disease Rat Model,FRONTIERS IN AGING NEUROSCIENCE 2018.
  • Virtual spatial navigation correlates with the moca score in amnestic mild cognitive impairment patients,JOURNAL OF THE NEUROLOGICAL SCIENCES 2017.
  • Asynchronous ripple oscillations between left and right hippocampi during slow-wave sleep,PLOS ONE 2017.
  • ANTI-INFLAMMATORY MESENCHYMAL STEM CELL-DERIVED SPHEROIDS INHIBIT CHRONIC AND RELAPSE-LIKE ETHANOL INTAKE AND REDUCE OXIDATIVE STRESS,ALCOHOL AND ALCOHOLISM 2017.
  • Regulation of Memory Formation by the Transcription Factor XBP1,

    CELL REPORTS 2016.

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